The forbidden ingredients this time round are so extensive that I am asking myself, to give you an analogy, how could a baker make bread without flour? Substituting some materials with others is an option but it is possible that some fragrances will never see the light of day. This has already happened to me three times.
— Serge Lutens, talking about IFRA regulations, in There’s a bad whiff about this fuss over fragrance at the London Evening Standard. Thanks to Anya for the link!